10 APRIL 2015 • VOL 348 ISSUE 6232 297 SCIENCE sciencemag.org
community was largely blindsided by the
2014 Ebola outbreak in West Africa. A
similar situation could arise in the MENA
region, but could be averted through
innovative and sustained programs of
vaccine science diplomacy and global
Peter J. Hotez
U.S. Science Envoy Program, Department of
State and White House, Washington, DC 20520,
USA; Sabin Vaccine Institute and Texas Children’s
Hospital Center for Vaccine Development, National
School of Tropical Medicine, Baylor College of
Medicine, Houston, TX 77030, USA; Department of
Biology, Baylor University, Waco, TX 76706, USA;
James A. Baker III Institute of Public Policy, Rice
University, Houston, TX 77005, USA.
REFERENCES AND NOTES
1. N.Salam, W.M.Al-Shaqha, A.Azzi, PLOSNegl. Trop.Dis.8,
2. S. Cousins, Lancet 385, 931 (2015).
3. P.J.Hotez, L.Savioli,A.Fenwick, PLOS Negl. Trop. Dis.6,
4. M.Gwidaetal.,Croat.Med.J.51, 289(2010).
5. UNICEF, Humanitarian Action for Children, Syrian
Refugees ( www.unicef.org/appeals/syrianrefugees.
6. Global Health.gov, Global Health Topics, The Global Health
Security Agenda ( www.globalhealth.gov/global-health-topics/global-health-security/ ghsagenda.html).
7. DCVMN ( www.dcvmn.org).
8. P. J. Hotez,PLOSNegl. Trop.Dis. 8, e2808 (2014).
9. The views presented herein are those of the author and
not necessarily those of the U.S. Department of State,
White House, or U.S. Government.
Comment on “Local reorganization of
xanthophores fine-tunes and colors the
striped pattern of zebrafish”
Masakatsu Watanabe and Shigeru Kondo
Mahalwar et al. (Reports, 12 September
2014, p. 1362) observed the onset of pigment pattern formation in zebrafish. They
concluded that their data do not support our
Turing mechanism–based model and presented an essentially different mechanism.
Here, we clarify their misunderstanding
that may have caused their conclusion and
explain past experimental data that do not
support their proposed mechanism.
Full text at http://dx.doi.org/10.1126/
Response to Comment on “Local
reorganization of xanthophores fine-tunes and colors the striped pattern
Ajeet Pratap Singh, Hans-Georg Frohnhöfer,
Uwe Irion, Christiane Nüsslein-Volhard
Watanabe and Kondo question our conclusion that the current Turing-type model
of color patterning in zebrafish requires
modification. In addition to xanthophores
and melanophores, iridophores are essential
for stripe formation in the body, although
not in the fins. A model of predictive value
should accommodate the in vivo dynamics
and interactions of all three chromatophore
types in body stripe formation.
Full text at http://dx.doi.org/10.1126/
OUTSIDE THE TOWER
More than a
Daniel, a smart and even-tempered boy of 15, lives in a humble neigh- borhood in the metropolitan area of Buenos Aires without access to Internet or even a phone in his
home. He has just completed a hands-
on activity in which he retraced the
steps leading Lavoisier to the discovery
of oxygen. He looks at me amazed, and
exclaims, “I understood things differently! I
felt like there was a strong wind inside my
head!” Iván, a shy but brilliant 17-year-old,
goes to one of the best public schools of
Argentina and participates regularly in
a range of science-related activities. He
turns to me after taking part in a spirited
stem cell debate and marvels, “I had the
chance to hear good arguments for ideas
that contradict my own. I’ve never had that
opportunity before.” Despite Daniel and
Iván’s disparate experiences, the pleasure
they felt when they found answers on their
own was the same.
Daniel, Iván, and another 38 boys and
girls from Argentina and other Latin
American countries were attending a
science camp held every February by
“Expedición Ciencia,” a nongovernmental
organization of scientists, educators, and
students devoted to promoting science
education for children in middle and high
school (1). When I was 16 years old, this
science camp changed my life. There, I
learned how to think scientifically, realized
I wanted to pursue a scientific career, and
above all forged unconditional friendships.
Today, as a passionate Ph.D. student in
immunology, I actively participate in this
NGO by helping to organize the camp and
serving as a junior counselor.
At Expedición Ciencia, we challenge
14- to 17-year-olds to ask questions about
nature as if they were the first ones in
history to do so. Through observation and
experiments, they follow the crucial steps
that lead to scientific breakthroughs and
learn the scientific method firsthand. But
something else happens in the meantime:
They become very close friends, break-
ing down social barriers and establishing
relationships that persist through time
Science not only allows us to see and
comprehend the world; it’s also a bridge
between people coming from different
backgrounds who share the same curiosity
and passion to understand the beautiful
world that surrounds us.
Luciano Gastón Morosi
Instituto de Biología y Medicina Experimental
(IBYME-CONICET), C1428ADN Buenos Aires,
Argentina. E-mail: firstname.lastname@example.org
Campers at Expedición Ciencia perform astronomical observations.
Outside the Tower is an occasional
feature highlighting science advocacy
projects led by scientists and citizen scientists. How do you advocate for science?
Tell us at submit2science.org.